Montalcino is a hill town and comune in Tuscany, Italy. It is famous for its Brunello di Montalcino wine. The town is located to the west of Pienza, close to the Crete Senesi in Val d’Orcia. It is 42 km from Siena, 110 km from Florence and 150 km from Pisa. The Monte Amiata is located nearby.